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Someone knows how to configure transport of diluted species?

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Hello, someone knows how to configure transport of diluted species?
I`m trying to simulate the diffusion of methanol in water. My model have two inputs and an output, microchannels. My question is i have to define the concentration of methanol and concentration of water at their respective model inputs or i have to define the methanol concentration and leave the water as 0?

thank you very much

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